Inhibitory potential of Japanese papaya (Cnidoscolus aconitifolius) leaf juice against the growth of Escherichia coli
DOI:
https://doi.org/10.35746/jsn.v3i2.858Kata Kunci:
Japanese pepaya leaves, antibacterial, Escherichia coliAbstrak
Indonesia is a country with high biodiversity that have many plants, one of them is japanesse pepaya plant (Cnidoscolus aconitifolius). Japanese pepaya leaves used by people as a traditional medicine, this is because pepaya leaves contain compounds that can act as antibacterials. Escherichia coli is a normal flora that found in the human large intestine (colon). Escherichia coli can cause primary infections, one of the infections is diarrhea. The purpose of this study was to determine the ability of Japanese pepaya leaf juice (Cnidoscolus aconitifolius) to inhibit the growth of Escherichia coli bacteria and to determine the concentration of Japanese pepaya leaf extract that is effective in inhibiting the growth of Escherichia coli bacteria. This type of research is a laboratory experiment. The inhibition test used the Kirby Bauer agar diffusion method. The research variables were the concentration of Japanese pepaya leaf extract of 25%, 50%, 75%, and 100%, and the growth inhibition zone of Escherichia coli bacteria. The results of this study showed that no inhibition zone formed around the wells when Japanese pepaya extract was administered at various concentrations. The conclusion of this study is that Japanese pepaya (Cnidoscolus aconitifolius) leaf juice has no potential to inhibit the growth of Escherichia coli bacteria.
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Ana L, F.-M., Walker, J. N., Caparon, M., & Hultgren, S. J. (2015). Urinary tract infections: epidemiology, mechanisms of infection and treatment options. Nature Reviews Microbiology, 13(May), 269–284. https://doi.org/10.1038/nrmicro3432.Urinary
Arza, P. A. (2022). Daun Pepaya Jepang.pdf. Madza Media.
Christi, R. F., Suharwanto, D., Ismiraj, M. R., & Salman, L. B. (2023). Peningkatan Produktivitas Kambing Perah Pasca Penyakit Mulut dan Kuku (PMK) Melalui Berbagai Upaya Manfaat Olahan Tanaman Herbal Fitofarmaka. Journal of Community Services, 04(2), 25–30. https://doi.org/10.24198/fjcs.v4i2.46180
Emelda, A., Yuliana, D., Maulana, A., Kurniawati, T., & Utamil, W. Y. (2023). Gambaran Penggunaan Antibiotik Pada Masyarakat Di Pasar Niaga Daya Makassar. Indonesian Journal of Community Dedication (IJCD), 5(1), 13–18. https://jurnal.stikesnh.ac.id/index.php/community/article/view/1007
Henly, E. L., Dowling, J. A. R., Maingay, J. B., Lacey, M. M., Smith, T. J., & Forbesa, S. (2019). Biocide Exposure Induces Changes in Susceptibility, Pathogenicity, and Biofilm Formation in Uropathogenic Escherichia coli. Antimicrobial Agents and Chemotherapy, 63(3), 1–15. https://doi.org/10.1128/aac.01892-18
Imawati, M. F., Hartanti, S. D., Puradewa, L., Katolik, U., & Mandala, W. (2023). Uji Aktivitas Antibakteri Ekstrak Daun Pepaya Jepang ( Cnidoscolus aconitifolius ) Dengan Metode Difusi Agar. Jurnal Ventilator: Jurnal Riset Ilmu Kesehatan Dan Keperawatan, 1(4), 378–384. https://doi.org/10.59680/ventilator.v1i4.839
Lestari, D. P. A. (2018). Perbedaan Daya Hambat Antara Antibiotik Amoxicillin dengan Perasan Daun Pepaya (Carica papaya L.) Terhadap Bakteri Staphylococcus aureus. Universitas Muhammadiyah Surabaya. https://repository.um-surabaya.ac.id/id/eprint/3316
Marta, F. D. (2024). Pengaruh Ekstrak Daun Pepaya Jepang (Cnidoscolus Aconitifolius) Yang Diekstraksi Dengan Beberapa Jenis Pelarut Dan Pemberian Konsentrasi Sebagai Biostimulan Terhadap Pertumbuhan Dan Hasil Jagung (Zea mays L.). Universitas Andalas. http://scholar.unand.ac.id/473407/
Nadiana, S. A. (2022). Analisis Metabolit Sekunder Daun Pepaya Jepang (Cnidoscolus aconitifolius) Pada Perbedaan Ketinggian Dengan Metode Gc-Ms. Universitas Pendidikan Indonesia.
Rohmah, I. A. N., & Amalia, I. D. (2024). Studi Pemanfaatan dan Peran Masyarakat Lokal terhadap Konservasi Tumbuhan Obat di Desa Cintamanis Baru , Kecamatan Air Kumbang , Banyuasin Sumatera Selatan. Prosiding Seminar Nasional Lahan Suboptimal Ke-12, 6051, 490–500. https://conference.unsri.ac.id/index.php/lahansuboptimal/article/view/3018
Shobah, A. N., Lidiah, M., & Stiani, S. N. (2023). Daya Hambat Ekstrak Etanol Daun Pepaya Jepang (Cnidoscolus aconitifolius) pada Fungi Candida albicans. Jurnal Kesehatan Perintis, 10(2), 94–105. https://doi.org/10.33653/jkp.v10i2.1001
Suzanni, M. A., Andalia, R., & Sauza, R. (2022). Aktivitas Antibakteri Ekstrak N -Heksan Daun Pepaya ( Carica papaya L ) Terhadap Escherichia coli dan Staphylococcus aureus. 2(2), 49–54. https://doi.org/10.56690/jskd.v2i2.67
Tuntun, M. (2016). Uji Efektivitas Ekstrak Daun Pepaya (Carica papaya L .) Terhadap Pertumbuhan Bakteri Escherichia coli dan Staphylococcus aureus. Jurnal Kesehatan, VII(3), 497–502. https://doi.org/10.26630/jk.v7i3.235
Ulfah, E. F. (2003). Pengaruh pemberian air perasan daun pepaya (Carica papaya L.) terhadap pertumbuhan bakteri Escherichia coli. Universitas Islam Negeri Maulana Malik Ibrahim. http://etheses.uin-malang.ac.id/57531/
Velioglu, A., Guneri, G., Arikan, H., Asicioglu, E., Tigen, E. T., Tanidir, Y., Tinay, ?., Yegen, C., & Tuglular, S. (2021). Incidence and risk factors for urinary tract infections in the first year after renal transplantation. PLoS ONE, 16(5 May), 1–11. https://doi.org/10.1371/journal.pone.0251036
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