Potensi Getah Patikan Kebo (Euphorbia hirta L.) dalam Menurunkan Waktu Perdarahan pada Luka Kulit Tikus Putih (Rattus norvegicus)
Abstract
Indonesia has many types of plants that are abundant and can be used as medicine. One of the plants used as medicine is patikan kebo (Euphorbia hirta L.) because it contains of several chemical compounds, which are tannin, flavonoid and saponin. Tannin and flavonoid are the main compounds in plants that help to stop the bleeding. The purpose of this study was to determine the potential of patikan kebo’s latex (Euphorbia hirta L.) to decrease the bleeding time in skin wounds of white rats (Rattus norvegicus). This research is a pre experiment. The number of experimental animals used was 10 which were divided into 2 treatment groups (T1 and T2). The treatment group T1)was not dripped with patikan kebo’s latex (Euphorbia hirta L.) and treatment group T2 was dripped with patikan kebo’s latex (Euphorbia hirta L.) and then the bleeding time was measured. Based on result of Independent Sample T Test showed that P value = 0,006 (P<0,05), it means the bleeding time in skin wound of white rats that were dripped with patikan kebo’s latex and without dripped with patikan kebo’s latex are significant.
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References
Fitriyah, L. (2011). PENGARUH GETAH POHON PISANG AMBON (Musa acuminate, L.) TERHADAP WAKTU PERDARAHAN, KOAGULASI DAN PENUTUPAN LUKA PADA MENCIT (Mus musculus). UIN SUNAN KALIJAGA YOGYAKARTA.
Notoatmodjo, S. (2010). Metodologi Penelitian Kesehatan. Rineka Cipta.
Prihantiny, L. S. (2010). Hubungan Pemberian Ekstrak Patikan Kebo (Euphorbia hirta L.) Terhadap Hitung Sel Mast Pada Mencit Balb/C Model Asma Alergi. Fakultas Kedokteran Universitas Sebelas Maret. Surakarta.
Purnamasari, O. & A. I. & B. T. (2012). Efek hemostatik ekstraketanol daunteratai (Nymphae rubra Roxb) pada luka potong ekor mencit (Mus musculus). Oral Biology Dent J. 2012 jan-jun;4 (1). 15–19.
Putra Satria, W. (2013). Sehat dengan Herbal Tanpa Dokter. Citra Media. Jakarta Selatan.
Sari, L., O. (2006). Pemanfaatan obat tradisional dengan pertimbangan manfaat dan keamanannya. Majalah Ilmu Kefarmasian. 3(1):1-7.
Tamril, R. (2014). Efek Antiperdarahan Alga Coklat (Sargassum sp. dan Padina sp.) pada Luka Potong Ekor Mencit (Mus Musculus) (Pilot Study). Makassar. 7–9.
Tedjasulaksana, R. (2013). Ekstrak etil asetat dan etanol daun sirih (Piper betle L.) dapat memperpendek waktu perdarahan mencit (Mus musculus). Jurnal Kesehatan gigi. 2013 Feb;1 (1). 32–39.
Yugasworo, V. (2014). Uji Efek Ekstrak Patikan Kebo (Euphorbia Hirta L) Sebagai Diuretik Pada Tikus Putih Jantan, Manado. 3(3), 287–293.
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